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Buy Caduet (Amlodipine Besylate, Atorvastatin Calcium) cardiovascular medication
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CADUET (AMLODIPINE BESYLATE, ATORVASTATIN CALCIUM) TABLETS: CONTRAINDICATIONS

Caduet contains atorvastatin and is therefore contraindicated in patients with active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels.

Caduet is contraindicated in patients with known hypersensitivity to any component of this medication.

Pregnancy and Lactation

Caduet contains atorvastatin and is therefore contraindicated in women who are pregnant or may become pregnant. The atorvastatin component of Caduet may cause fetal harm when administered to a pregnant woman. Serum cholesterol and triglycerides increase during normal pregnancy, and cholesterol or cholesterol derivatives are essential for fetal development. Atherosclerosis is a chronic process and discontinuation of lipid25 lowering drugs during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia.

There are no adequate and well-controlled studies of atorvastatin use during pregnancy; however in rare reports congenital anomalies were observed following intrauterine exposure to statins. In rat and rabbit animal reproduction studies, atorvastatin revealed no evidence of teratogenicity. Caduet, which includes atorvastatin, should be administered to women of childbearing age only when such patients are highly unlikely to conceive and have been informed of the potential hazards. If the patient becomes pregnant while taking this drug, therapy should be discontinued immediately and the patient apprised of the potential hazard to the fetus.

It is not known whether atorvastatin or amlodipine are excreted into human milk; however a small amount of another statin does pass into breast milk. Because statins have the potential for serious adverse reactions in nursing infants, women taking Caduet should not breastfeed their infants.



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